3RWR

Crystal structure of the human XRCC4-XLF complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, F, G, J...	DNA repair protein XRCC4	polymer	163	18869.1	12	UniProt (Q13426) Pfam (PF06632) In PDB	Homo sapiens (human)	X-ray repair cross-complementing protein 4
2	D, E, H, I, L...	Non-homologous end-joining factor 1	polymer	230	26286.3	12	UniProt (Q9H9Q4) Pfam (PF09302) In PDB	Homo sapiens (human)	Protein cernunnos, XRCC4-like factor
3	J, M, P, V, X...	HEXATANTALUM DODECABROMIDE	non-polymer		2044.5	8	Chemie (TBR)

Sequence modifications

A, B, F, G, J, K, N, P, R, V, U, Y: 1 - 157 (UniProt: Q13426)

PDB	External Database	Details
His 158	-	expression tag
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag

D, E, H, I, L, M, O, Q, S, W, T, X: 1 - 224 (UniProt: Q9H9Q4)

PDB	External Database	Details
His 225	-	expression tag
His 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	541865.7
Non-Polymers*	Number of molecules	8
	Total formula weight	16356.3
All*	Total formula weight	558221.9

*Water molecules are not included.