3RVY

Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.7 A)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ion transport protein	polymer	285	33105.1	2	UniProt (A8EVM5) Pfam (PF00520) Pfam (PF08016)	Arcobacter butzleri
2	C, D, E, F, G... (A, B)	1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		678.9	10	Chemie (PX4)
3	M, N (A, B)	water	water		18.0	2	Chemie (HOH)

Sequence modifications

A, B: 1001 - 1267 (UniProt: A8EVM5)

PDB	External Database	Details
Met 983	-	expression tag
Asp 984	-	expression tag
Tyr 985	-	expression tag
Lys 986	-	expression tag
Asp 987	-	expression tag
Asp 988	-	expression tag
Asp 989	-	expression tag
Asp 990	-	expression tag
Lys 991	-	expression tag
Gly 992	-	expression tag
Ser 993	-	expression tag
Leu 994	-	expression tag
Val 995	-	expression tag
Pro 996	-	expression tag
Arg 997	-	expression tag
Gly 998	-	expression tag
Ser 999	-	expression tag
His 1000	-	expression tag
Cys 1217	Ile 217	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66210.2
Non-Polymers*	Number of molecules	10
	Total formula weight	6789.4
All*	Total formula weight	72999.6

*Water molecules are not included.