3RVY

Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.7 A)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001518	cellular_component	voltage-gated sodium channel complex
A	0005216	molecular_function	monoatomic ion channel activity
A	0005248	molecular_function	voltage-gated sodium channel activity
A	0005261	molecular_function	monoatomic cation channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0035725	biological_process	sodium ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0055085	biological_process	transmembrane transport
A	0098655	biological_process	monoatomic cation transmembrane transport
B	0001518	cellular_component	voltage-gated sodium channel complex
B	0005216	molecular_function	monoatomic ion channel activity
B	0005248	molecular_function	voltage-gated sodium channel activity
B	0005261	molecular_function	monoatomic cation channel activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0035725	biological_process	sodium ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0055085	biological_process	transmembrane transport
B	0098655	biological_process	monoatomic cation transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 4001

Chain	Residue
A	MET1137
A	GLY1164
B	TRP2195

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 A 4003

Chain	Residue
B	SER2034

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 4005

Chain	Residue
A	SER1132
B	GLN2115
B	MET2116

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 A 4013

Chain	Residue
A	SER1034

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 4015

Chain	Residue
A	MET1116
B	SER2132
A	GLN1115

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 B 4002

Chain	Residue
B	TYR2191

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site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 B 4011

Chain	Residue
A	TRP1195
B	MET2137
B	GLY2164
B	GLU2165
B	PHE2167

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site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 B 4012

Chain	Residue
A	TYR1191

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