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3RTF

Chlorowillardiine bound to the ligand binding domain of GluA2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(B, D, F)
Glutamate receptor 2polymer25828835.33UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (rat)GluA2, GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2
2D, G, J
(B, D, F)
3-(5-chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alaninenon-polymer233.63Chemie (CWD)
3E, F, H, I, K
(B, D, F)
ZINC IONnon-polymer65.45Chemie (ZN)
4L, M, N
(B, D, F)
waterwater18.01043Chemie (HOH)
Sequence modifications
B, D, F: 4 - 117 (UniProt: P19491)
B, D, F: 120 - 261 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 118-linker
Thr 119-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight86506.0
Non-Polymers*Number of molecules8
Total formula weight1027.9
All*Total formula weight87533.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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