3RPG

Bmi1/Ring1b-UbcH5c complex structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ubiquitin-conjugating enzyme E2 D3	polymer	149	16832.2	1	UniProt (P61077) Pfam (PF00179)	Homo sapiens (human)	Ubiquitin carrier protein D3, Ubiquitin-conjugating enzyme E2(17)KB 3, Ubiquitin-conjugating enzyme E2-17 kDa 3, Ubiquitin-protein ligase D3
2	B (B)	Polycomb complex protein BMI-1	polymer	117	13654.0	1	UniProt (P35226) Pfam (PF13923)	Homo sapiens (human)	Polycomb group RING finger protein 4, RING finger protein 51
3	C (C)	E3 ubiquitin-protein ligase RING2	polymer	121	13514.7	1	UniProt (Q99496) Pfam (PF13923)	Homo sapiens (human)	Huntingtin-interacting protein 2-interacting protein 3, HIP2-interacting protein 3, Protein DinG, RING finger protein 1B, RING1b, RING finger protein 2, RING finger protein BAP-1
4	D, E, F, G (B, C)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
5	H, I, J (A, B, C)	water	water		18.0	115	Chemie (HOH)

Sequence modifications

A: 2 - 147 (UniProt: P61077)

PDB	External Database	Details
Leu -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag

B: 1 - 109 (UniProt: P35226)

PDB	External Database	Details
Leu 110	-	expression tag
Glu 111	-	expression tag
His 112	-	expression tag
His 113	-	expression tag
His 114	-	expression tag
His 115	-	expression tag
His 116	-	expression tag
His 117	-	expression tag

C: 1 - 116 (UniProt: Q99496)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	44000.9
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	44262.6

*Water molecules are not included.