3RNU
Structural Basis of Cytosolic DNA Sensing by Innate Immune Receptors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Gamma-interferon-inducible protein 16 | polymer | 204 | 22896.3 | 4 | UniProt (Q16666) Pfam (PF02760) In PDB | Homo sapiens (human) | Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator |
2 | K | DNA (5'-D(*GP*CP*CP*AP*TP*CP*AP*AP*AP*GP*AP*GP*AP*GP*AP*G)-3') | polymer | 16 | 4965.3 | 1 | |||
3 | L | DNA (5'-D(*TP*CP*TP*CP*TP*CP*TP*TP*TP*GP*AP*TP*GP*GP*CP*C)-3') | polymer | 16 | 4831.1 | 1 | |||
4 | A, B, C, D | FORMIC ACID | non-polymer | 46.0 | 5 | Chemie (FMT) | |||
5 | B, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
6 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 571 - 766 (UniProt: Q16666)
PDB | External Database | Details |
---|---|---|
Gly 567 | - | expression tag |
Ser 568 | - | expression tag |
Val 569 | - | expression tag |
Asp 570 | - | expression tag |
Ala 767 | - | expression tag |
Ala 768 | - | expression tag |
Ala 769 | - | expression tag |
Ser 770 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 101381.5 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 354.3 | |
All* | Total formula weight | 101735.7 |