3RNU
Structural Basis of Cytosolic DNA Sensing by Innate Immune Receptors
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002218 | biological_process | activation of innate immune response |
| A | 0035458 | biological_process | cellular response to interferon-beta |
| B | 0002218 | biological_process | activation of innate immune response |
| B | 0035458 | biological_process | cellular response to interferon-beta |
| C | 0002218 | biological_process | activation of innate immune response |
| C | 0035458 | biological_process | cellular response to interferon-beta |
| D | 0002218 | biological_process | activation of innate immune response |
| D | 0035458 | biological_process | cellular response to interferon-beta |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 6 |
| Chain | Residue |
| A | ARG721 |
| A | HIS757 |
| A | ILE758 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 2 |
| Chain | Residue |
| B | PRO646 |
| B | THR648 |
| B | LEU649 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT B 4 |
| Chain | Residue |
| B | ILE758 |
| B | ARG721 |
| B | LEU722 |
| B | HIS757 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT C 3 |
| Chain | Residue |
| C | ARG721 |
| C | LEU722 |
| C | HIS757 |
| C | ILE758 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 1 |
| Chain | Residue |
| D | HOH34 |
| D | PRO646 |
| D | THR648 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT D 5 |
| Chain | Residue |
| D | PHE589 |
| D | ARG721 |
| D | LEU722 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT D 7 |
| Chain | Residue |
| D | ARG638 |
| D | ASN639 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"22691496","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 195 |
| Details | Region: {"description":"Interaction with TP53 core domain"} |
| Chain | Residue | Details |
