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3RNJ

Crystal structure of the SH3 domain from IRSp53 (BAIAP2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Brain-specific angiogenesis inhibitor 1-associated protein 2polymer677512.51UniProt (Q9UQB8)
Pfam (PF07653)
Homo sapiens (human)BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, FLAF3, Insulin receptor substrate p53/p58, IRS-58, IRSp53/58, Insulin receptor substrate protein of 53 kDa, IRSp53, Insulin receptor substrate p53
2B
(A)
{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACIDnon-polymer292.21Chemie (EDT)
3C, D, E
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4F
(A)
ISOPROPYL ALCOHOLnon-polymer60.11Chemie (IPA)
5G
(A)
waterwater18.086Chemie (HOH)
Sequence modifications
A: 375 - 436 (UniProt: Q9UQB8)
PDBExternal DatabaseDetails
Gly 370-expression tag
Pro 371-expression tag
Leu 372-expression tag
Gly 373-expression tag
Ser 374-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight7512.5
Non-Polymers*Number of molecules5
Total formula weight538.5
All*Total formula weight8051.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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