3RMC

Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	DNA polymerase	polymer	906	105069.6	4	UniProt (Q38087) Pfam (PF03104) Pfam (PF00136)	Enterobacteria phage RB69	Gp43
2	E, G, I, K (E, G, I, K)	DNA (5'-D(*CP*GP*TP*(CTG)P*GP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3')	polymer	18	5575.6	4
3	F, H, J, L (F, H, J, L)	DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*CP*A)-3')	polymer	14	4271.8	4
4	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	121	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 903 (UniProt: Q38087)

PDB	External Database	Details
Ala 222	Asp 222	engineered mutation
Ala 327	Asp 327	engineered mutation
His 904	-	expression tag
His 905	-	expression tag
His 906	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	459667.9
All*	Total formula weight	459667.9

*Water molecules are not included.