3RIE
The structure of Plasmodium falciparum spermidine synthase in complex with 5'-methylthioadenosine and N-(3-aminopropyl)-trans-cyclohexane-1,4-diamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spermidine synthase | polymer | 283 | 32221.2 | 3 | UniProt (Q8II73) Pfam (PF17284) Pfam (PF01564) | Plasmodium falciparum | |
| 2 | D, G, K (A, B, C) | 5'-DEOXY-5'-METHYLTHIOADENOSINE | non-polymer | 297.3 | 3 | Chemie (MTA) PubChem (25322898) PubChem (40467850) PubChem (44264468) PubChem (46874793) PubChem (51397471) PubChem (51397472) PubChem (57104771) PubChem (99302) PubChem (58108938) PubChem (58682801) PubChem (453683) PubChem (59099797) PubChem (98100246) PubChem (149) PubChem (91614589) PubChem (439176) PubChem (688097) PubChem (124300729) PubChem (124300795) PubChem (6541356) PubChem (134694842) PubChem (138107656) PubChem (13101165) PubChem (13101166) PubChem (164077596) | |||
| 3 | E, H, L (A, B, C) | trans-N-(3-aminopropyl)cyclohexane-1,4-diamine | non-polymer | 171.3 | 3 | Chemie (JFQ) PubChem (19004811) | |||
| 4 | F, I, M (A, B, C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) PubChem (753) | |||
| 5 | J (C) | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL | non-polymer | 252.3 | 1 | Chemie (1PG) PubChem (90255) | |||
| 6 | N, O, P (A, B, C) | water | water | 18.0 | 617 | Chemie (HOH) |
Sequence modifications
A, B, C: 41 - 321 (UniProt: Q8II73)
| PDB | External Database | Details |
|---|---|---|
| Gly 39 | - | expression tag |
| Ser 40 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 96663.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1934.4 | |
| All* | Total formula weight | 98597.9 |
