3RIA
C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and iodide.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | Avermectin-sensitive glutamate-gated chloride channel GluCl alpha | polymer | 347 | 39636.6 | 5 | UniProt (O17793) In PDB | Caenorhabditis elegans (nematode) | |
2 | F, G, H, I, J | Mouse monoclonal Fab fragment, heavy chain | polymer | 221 | 23921.7 | 5 | Mus musculus (mouse) | ||
3 | K, L, M, N, O | Mouse monoclonal Fab fragment, light chain | polymer | 210 | 22618.2 | 5 | Mus musculus (mouse) | ||
4 | E, A, C | (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside | non-polymer | 875.1 | 5 | Chemie (IVM) | |||
5 | A, B | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 3 | Chemie (LMT) | |||
6 | D, E, A, B | IODIDE ION | non-polymer | 126.9 | 4 | Chemie (IOD) | |||
7 | D, E, B | N-OCTANE | non-polymer | 114.2 | 3 | Chemie (OCT) | |||
8 | B | UNDECANE | non-polymer | 156.3 | 1 | Chemie (UND) | |||
9 | C | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) |
Sequence modifications
A, B, C, D, E: 1 - 302 (UniProt: O17793)
A, B, C, D, E: 312 - 338 (UniProt: O17793)
PDB | External Database | Details |
---|---|---|
His 340 | - | expression tag |
His 341 | - | expression tag |
His 342 | - | expression tag |
His 343 | - | expression tag |
His 344 | - | expression tag |
His 345 | - | expression tag |
His 346 | - | expression tag |
His 347 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 303 | - | linker |
Gly 304 | - | linker |
Thr 305 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 15 |
Total formula weight | 430882.6 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 6949.4 | |
All* | Total formula weight | 437832.0 |