3RI0
Epitope backbone grafting by computational design for improved presentation of linear epitopes on scaffold proteins
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | BB_2cx5_001 | polymer | 165 | 17308.7 | 2 | UniProt (Q5SHN1) Pfam (PF04073) In PDB | Thermus thermophilus | |
2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
3 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 81 (UniProt: Q5SHN1)
A, B: 95 - 158 (UniProt: Q5SHN1)
PDB | External Database | Details |
---|---|---|
Ala 53 | Val 53 | engineered mutation |
Tyr 54 | Phe 54 | engineered mutation |
Gly 55 | Val 55 | engineered mutation |
Ser 57 | Glu 57 | engineered mutation |
Ala 77 | Thr 77 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ala 100 | Ile 100 | engineered mutation |
Leu 159 | - | insertion |
Glu 160 | - | insertion |
His 161 | - | expression tag |
His 162 | - | expression tag |
His 163 | - | expression tag |
His 164 | - | expression tag |
His 165 | - | expression tag |
His 166 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 34617.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 188.2 | |
All* | Total formula weight | 34805.6 |