3RGV
A single TCR bound to MHCI and MHC II reveals switchable TCR conformers
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Yae62 TCR a chain | polymer | 200 | 22206.3 | 1 | Mus musculus (mouse) | ||
| 2 | B | Yae62 TCR b chain | polymer | 236 | 26471.3 | 1 | Mus musculus (mouse) | ||
| 3 | C | H-2 class I histocompatibility antigen, K-B alpha chain | polymer | 275 | 31701.3 | 1 | UniProt (P01901) Pfam (PF00129) Pfam (PF07654) In PDB | Mus musculus (mouse) | H-2K(B) |
| 4 | D | Beta-2-microglobulin | polymer | 100 | 11761.4 | 1 | UniProt (P01887) Pfam (PF07654) In PDB | Mus musculus (mouse) | |
| 5 | E | peptide | polymer | 13 | 1489.7 | 1 | Mus musculus (mouse) |
Sequence modifications
C: 1 - 275 (UniProt: P01901)
D: 1 - 99 (UniProt: P01887)
| PDB | External Database | Details |
|---|---|---|
| Cys 84 | Tyr 105 | engineered mutation |
| Ser 121 | Cys 142 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 93630.1 | |
| All* | Total formula weight | 93630.1 |
