3REP
Crystal structure of the ILK/alpha-parvin core complex (MnATP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin-linked kinase | polymer | 271 | 30972.0 | 1 | UniProt (Q13418) Pfam (PF07714) | Homo sapiens (human) | ILK |
| 2 | B (B) | Alpha-parvin | polymer | 129 | 14843.1 | 1 | UniProt (Q9NVD7) Pfam (PF00307) | Homo sapiens (human) | Actopaxin, CH-ILKBP, Calponin-like integrin-linked kinase-binding protein, Matrix-remodeling-associated protein 2 |
| 3 | C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 4 | D (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 328 | Chemie (HOH) |
Sequence modifications
A: 183 - 452 (UniProt: Q13418)
B: 248 - 372 (UniProt: Q9NVD7)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Ser 346 | Cys 346 | engineered mutation |
| Ser 422 | Cys 422 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| His -2 | - | expression tag |
| Met -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45815.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 562.1 | |
| All* | Total formula weight | 46377.2 |
