3REP

Crystal structure of the ILK/alpha-parvin core complex (MnATP)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation
B	0003779	molecular_function	actin binding
B	0007155	biological_process	cell adhesion
B	0030036	biological_process	actin cytoskeleton organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 501

Chain	Residue
A	HOH22
A	HOH78
A	ASP339
A	ATP502

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site_id	AC2
Number of Residues	27
Details	BINDING SITE FOR RESIDUE ATP A 502

Chain	Residue
A	HOH91
A	HOH96
A	HOH112
A	HOH177
A	ASN200
A	ASN202
A	HIS203
A	SER204
A	LEU207
A	VAL218
A	LYS220
A	THR269
A	HIS270
A	TRP271
A	MET272
A	ASN279
A	ARG323
A	MET326
A	ASP339
A	LYS341
A	HOH468
A	MN501
A	HOH5
A	HOH22
A	HOH26
A	HOH53
A	HOH78

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:20005845, ECO:0000269|PubMed:21524996, ECO:0007744|PDB:3KMW, ECO:0007744|PDB:3REP

Chain	Residue	Details
A	ASN200
A	ASN202
A	SER204
A	LYS220
A	HIS270
A	MET272
A	ASN279
A	LYS341

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:21524996, ECO:0007744|PDB:3REP

Chain	Residue	Details
A	HIS203

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:20005845, ECO:0007744|PDB:3KMW

Chain	Residue	Details
A	ASP339

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
A	SER186

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PAK1 => ECO:0000269|PubMed:17420447

Chain	Residue	Details
A	SER246

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:O55222

Chain	Residue	Details
A	LYS426

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