3REK

2.6 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Oxaliplatin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Histone H3.2	polymer	135	15303.9	2	UniProt (P84233) Pfam (PF00125) In PDB	Xenopus laevis (clawed frog common platanna platanna)
2	B, F	Histone H4	polymer	102	11263.2	2	UniProt (P62799) Pfam (PF15511) In PDB	Xenopus laevis (clawed frog common platanna platanna)
3	C, G	Histone H2A type1	polymer	129	13978.2	2	UniProt (P06897) Pfam (PF00125) Pfam (PF16211) In PDB	Xenopus laevis (clawed frog common platanna platanna)
4	D, H	Histone H2B 1.1	polymer	122	13524.8	2	UniProt (P02281) Pfam (PF00125) In PDB	Xenopus laevis (clawed frog common platanna platanna)	H2B1
5	I, J	DNA (146-MER)	polymer	146	45054.8	2		Homo sapiens
6	A, D	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
7	I, J, A, B, E...	PLATINUM (II) ION	non-polymer		195.1	40	Chemie (PT)
8	C, D, G	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)

Sequence modifications

A, E: 1 - 135 (UniProt: P84233)

PDB	External Database	Details
Ala 102	Gly 103	variant

C, G: 1 - 129 (UniProt: P06897)

PDB	External Database	Details
Arg 99	Gly 100	variant
Ser 123	Ala 124	variant

D, H: 1 - 122 (UniProt: P02281)

PDB	External Database	Details
Thr 29	Ser 33	variant

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	198250.0
Non-Polymers*	Number of molecules	45
	Total formula weight	8201.2
All*	Total formula weight	206451.2

*Water molecules are not included.