3R68

Molecular Analysis of the PDZ3 domain of PDZK1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Na(+)/H(+) exchange regulatory cofactor NHE-RF3	polymer	95	10241.6	1	UniProt (Q9JIL4) Pfam (PF00595)	Mus musculus (mouse)	NHERF-3, CFTR-associated protein of 70 kDa, Na(+)/H(+) exchanger regulatory factor 3, Na/Pi cotransporter C-terminal-associated protein 1, NaPi-Cap1, PDZ domain-containing protein 1, Sodium-hydrogen exchanger regulatory factor 3
2	B, C (A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
3	D (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	E, F, G, H (A)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
5	I, J, K, L, N (A)	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
6	M, O (A)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
7	P (A)	water	water		18.0	116	Chemie (HOH)

Sequence modifications

A: 238 - 323 (UniProt: Q9JIL4)

PDB	External Database	Details
Gly 236	-	expression tag
Ser 237	-	expression tag
Leu 324	-	expression tag
Glu 325	-	expression tag
Arg 326	-	expression tag
Pro 327	-	expression tag
His 328	-	expression tag
Arg 329	-	expression tag
Asp 330	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	10241.6
Non-Polymers*	Number of molecules	14
	Total formula weight	699.2
All*	Total formula weight	10940.8

*Water molecules are not included.