3QZS
Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nucleosome-remodeling factor subunit BPTF | polymer | 115 | 13385.2 | 2 | UniProt (Q12830) Pfam (PF00439) | Homo sapiens (human) | Bromodomain and PHD finger-containing transcription factor, Fetal Alz-50 clone 1 protein, Fetal Alzheimer antigen |
| 2 | C, D (C, D) | Histone H4 | polymer | 10 | 1183.4 | 2 | UniProt (P62805) | Xenopus laevis | |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence modifications
A, B: 65 - 174 (UniProt: Q12830)
| PDB | External Database | Details |
|---|---|---|
| Gly 60 | - | expression tag |
| Pro 61 | - | expression tag |
| Leu 62 | - | expression tag |
| Gly 63 | - | expression tag |
| Ser 64 | - | expression tag |
| Ala 139 | Lys 2998 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 29137.3 | |
| All* | Total formula weight | 29137.3 |
