3QT4

Structure of digestive procathepsin L 3 of Tenebrio molitor larval midgut

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Cathepsin-L-like midgut cysteine proteinase	polymer	329	36483.0	1	UniProt (Q7YXL2) Pfam (PF08246) Pfam (PF00112)	Tenebrio molitor (Yellow mealworm beetle)
2	B, C, D, E, F... (A)	PHOSPHATE ION	non-polymer		95.0	10	Chemie (PO4)
3	L, M, N, O, P... (A)	TETRAETHYLENE GLYCOL	non-polymer		194.2	7	Chemie (PG4)
4	S, T (A)	1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE	non-polymer		266.3	2	Chemie (PG6)
5	U (A)	water	water		18.0	262	Chemie (HOH)

Sequence modifications

A: 1 - 312 (UniProt: Q7YXL2)

PDB	External Database	Details
Met -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Asp -5	-	expression tag
Leu -4	-	expression tag
Glu -3	-	expression tag
Ile -2	-	expression tag
Cys -1	-	expression tag
Ser 0	-	expression tag
Ser 122	Cys 140	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36483.0
Non-Polymers*	Number of molecules	19
	Total formula weight	2842.0
All*	Total formula weight	39325.0

*Water molecules are not included.