3QLR
Candida albicans dihydrofolate reductase complexed with NADPH and 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine (UCP112A)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Putative uncharacterized protein CaJ7.0360 | polymer | 192 | 22194.5 | 2 | UniProt (Q5A5E0) Pfam (PF00186) UniProt (by SIFTS) (P22906) | Candida albicans (yeast) | Putative uncharacterized protein DFR1 |
| 2 | C, H (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, I (A, B) | 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine | non-polymer | 356.4 | 2 | Chemie (QLR) | |||
| 4 | E, J (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F, G (A) | GLYCINE | non-polymer | 75.1 | 2 | Chemie (GLY) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 192 (UniProt: Q5A5E0)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Leu 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44389.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2538.0 | |
| All* | Total formula weight | 46927.1 |
