3QLN

Crystal structure of ATRX ADD domain in free state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Transcriptional regulator ATRX	polymer	129	14793.9	2	UniProt (P46100) Pfam (PF17981) In PDB	Homo sapiens (human)	ATP-dependent helicase ATRX, X-linked helicase II, X-linked nuclear protein, XNP, Znf-HX
2	A, B	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3		water	water		18.0	334	Chemie (HOH)

Sequence modifications

A, B: 167 - 289 (UniProt: P46100)

PDB	External Database	Details
Gly 161	-	expression tag
Pro 162	-	expression tag
Leu 163	-	expression tag
Gly 164	-	expression tag
Ser 165	-	expression tag
Met 166	-	expression tag
Arg 251	Lys 251	engineered mutation
Tyr 284	Phe 284	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29587.7
Non-Polymers*	Number of molecules	6
	Total formula weight	392.5
All*	Total formula weight	29980.2

*Water molecules are not included.