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3QKJ

The PWWP domain of human DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3 BETA in complex with a bis-tris molecule

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
DNA cytosine-5 methyltransferase 3 beta isoform 6 variantpolymer15116755.94UniProt (Q59H79)
Pfam (PF00855)
UniProt (by SIFTS) (Q9UBC3)
Homo sapiens (human)
2E, H, K, L
(A, B, C, D)
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer209.24Chemie (BTB)
3F, G, I, J, M...
(A, B, D)
SULFATE IONnon-polymer96.16Chemie (SO4)
4O, P, Q, R
(A, B, C, D)
waterwater18.0263Chemie (HOH)
Sequence modifications
A, B, C, D: 206 - 355 (UniProt: Q59H79)
PDBExternal DatabaseDetails
Gly 205-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight67023.6
Non-Polymers*Number of molecules10
Total formula weight1413.3
All*Total formula weight68436.9
*Water molecules are not included.

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PDB entries from 2026-01-14

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