3QKJ

The PWWP domain of human DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3 BETA in complex with a bis-tris molecule

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE BTB A 356

Chain	Residue
A	ILE233
A	PHE236
A	TRP239
A	TRP263
A	ASP266
A	LYS268
A	HOH362

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 3

Chain	Residue
A	ASN351
A	LYS308
A	ARG312

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 4

Chain	Residue
A	ARG310
A	THR316
D	LYS234

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BTB B 356

Chain	Residue
B	HOH3
B	ILE233
B	PHE236
B	TRP263
B	ASP266

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 5

Chain	Residue
B	LYS300
C	ARG252

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 B 6

Chain	Residue
B	ARG252

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE BTB C 356

Chain	Residue
C	ILE233
C	TRP239
C	TRP263
C	ASP266
C	LYS268
C	HOH367

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE BTB D 356

Chain	Residue
D	HOH134
D	ILE233
D	PHE236
D	TRP239
D	TRP263
D	ASP266
D	LYS268

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 1

Chain	Residue
C	LYS232
C	TRP238
C	HOH361
C	HOH364
D	LYS232
D	TRP238

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 2

Chain	Residue
D	LYS251
D	ARG252
D	HOH360

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	232
Details	Domain: {"description":"PWWP","evidences":[{"source":"PROSITE-ProRule","id":"PRU00162","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---