3QFX
Trypanosoma brucei dihydrofolate reductase pyrimethamine complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 241 | 26307.5 | 2 | Pfam (PF00186) UniProt (by SIFTS) (Q27783) | Trypanosoma brucei rhodesiense | DHFR-TS, Dihydrofolate reductase, Thymidylate synthase |
| 2 | C, E (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, F (A, B) | 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE | non-polymer | 248.7 | 2 | Chemie (CP6) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 343 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52614.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1988.3 | |
| All* | Total formula weight | 54603.2 |
