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3QEH

Crystal structure of human N12-i15, an ADCC and non-neutralizing anti-HIV-1 Env antibody

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, C, E, G)
Fab fragment of human anti-HIV-1 Env antibody N12-i15, heavy chainpolymer23225036.14Homo sapiens (human)
2B, D, F, H
(B, D, F, H)
Fab fragment of human anti-HIV-1 Env antibody N12-i15,light chainpolymer21823843.64Homo sapiens (human)
3I, R, V
(A, E, G)
SULFATE IONnon-polymer96.13Chemie (SO4)
4J, K, L, M, N...
(A, B, C, D, F...)
CHLORIDE IONnon-polymer35.510Chemie (CL)
5P, S, T, X
(D, E, F, H)
GLYCEROLnon-polymer92.14Chemie (GOL)
6AA, BA, CA, DA, EA...
(B, C, D, E, F...)
waterwater18.0566Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight195518.8
Non-Polymers*Number of molecules17
Total formula weight1011.1
All*Total formula weight196529.9
*Water molecules are not included.

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PDB entries from 2025-07-02

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