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3QEB

Crystal structure of human exonuclease 1 Exo1 (WT) in complex with DNA and Mn2+ (complex III)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(Z)
Exonuclease 1polymer35239559.91UniProt (Q9UQ84)
Pfam (PF00752)
Pfam (PF00867)
Homo sapiens (human)hExo1, Exonuclease I, hExoI
2B
(A)
DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3')polymer133951.61
3C
(B)
DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3')polymer103045.01
4D, E
(Z)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
5F, G, H
(Z, A, B)
waterwater18.016Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight46556.5
Non-Polymers*Number of molecules2
Total formula weight109.9
All*Total formula weight46666.4
*Water molecules are not included.

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PDB entries from 2024-10-30

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