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3QCZ

Crystal structure of bifunctional folylpolyglutamate synthase/dihydrofolate synthase with Mn, AMPPNP and L-Glutamate bound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydrofolate synthase / folylpolyglutamate synthasepolymer43747550.71UniProt (Q0WDC2)
Pfam (PF08245)
Pfam (PF02875)
UniProt (by SIFTS) (A0A5P8YIK0)
Yersinia pestis
2B
(A)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
3C
(A)
MANGANESE (II) IONnon-polymer54.91Chemie (MN)
4D, E
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
5F
(A)
GLUTAMIC ACIDnon-polymer147.11Chemie (GLU)
6G
(A)
waterwater18.0205Chemie (HOH)
Sequence modifications
A: 1 - 434 (UniProt: Q0WDC2)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight47550.7
Non-Polymers*Number of molecules5
Total formula weight892.5
All*Total formula weight48443.1
*Water molecules are not included.

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PDB entries from 2025-07-23

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