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3QBT

Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, C, E, G)
Ras-related protein Rab-8Apolymer17420012.04UniProt (P61006)
Pfam (PF00071)
Homo sapiens (human)Oncogene c-mel
2E, F, G, H
(B, D, F, H)
Inositol polyphosphate 5-phosphatase OCRL-1polymer14016554.74UniProt (Q01968)
Pfam (PF21310)
Homo sapiens (human)Lowe oculocerebrorenal syndrome protein
3I, K, M, O
(A, C, E, G)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
4J, L, N, P
(A, C, E, G)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.24Chemie (GNP)
5Q, R
(B, D)
SULFATE IONnon-polymer96.12Chemie (SO4)
6S, T, U, V, W...
(A, C, E, G, B...)
waterwater18.0308Chemie (HOH)
Sequence modifications
A, C, E, G: 6 - 176 (UniProt: P61006)
PDBExternal DatabaseDetails
Gly 3-expression tag
His 4-expression tag
Met 5-expression tag
B, D, F, H: 540 - 678 (UniProt: Q01968)
PDBExternal DatabaseDetails
Gly 539-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight146266.8
Non-Polymers*Number of molecules10
Total formula weight2378.1
All*Total formula weight148644.9
*Water molecules are not included.

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PDB entries from 2024-10-30

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