3QBT

Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	Ras-related protein Rab-8A	polymer	174	20012.0	4	UniProt (P61006) Pfam (PF00071) In PDB	Homo sapiens (human)	Oncogene c-mel
2	B, D, F, H	Inositol polyphosphate 5-phosphatase OCRL-1	polymer	140	16554.7	4	UniProt (Q01968) Pfam (PF21310) In PDB	Homo sapiens (human)	Lowe oculocerebrorenal syndrome protein
3	A, C, E, G	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	A, C, E, G	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	4	Chemie (GNP)
5	B, D	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6		water	water		18.0	308	Chemie (HOH)

Sequence modifications

A, C, E, G: 6 - 176 (UniProt: P61006)

PDB	External Database	Details
Gly 3	-	expression tag
His 4	-	expression tag
Met 5	-	expression tag

B, D, F, H: 540 - 678 (UniProt: Q01968)

PDB	External Database	Details
Gly 539	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	146266.8
Non-Polymers*	Number of molecules	10
	Total formula weight	2378.1
All*	Total formula weight	148644.9

*Water molecules are not included.