3Q8W

A b-aminoacyl containing thiazolidine derivative and DPPIV complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dipeptidyl peptidase 4	polymer	732	85081.2	2	UniProt (P27487) Pfam (PF00930) Pfam (PF00326)	Homo sapiens (human)	ADABP, Adenosine deaminase complexing protein 2, ADCP-2, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV soluble form
2	C, D (A, B)	N-(4-{[({(2R)-3-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-1,3-thiazolidin-2-yl}carbonyl)amino]methyl}phenyl)-D-valine	non-polymer		552.6	2	Chemie (AZV)

Sequence modifications

A, B: 39 - 764 (UniProt: P27487)

PDB	External Database	Details
His 765	-	expression tag
His 766	-	expression tag
His 767	-	expression tag
His 768	-	expression tag
His 769	-	expression tag
His 770	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	170162.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1105.2
All*	Total formula weight	171267.7

*Water molecules are not included.