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3Q8S

Human DNA polymerase iota incorporating dTTP opposite 8-oxo-guanine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
DNA polymerase iotapolymer42047027.31UniProt (Q9UNA4)
Pfam (PF00817)
Pfam (PF21999)
Pfam (PF11799)
Homo sapiens (human)Eta2, RAD30 homolog B
2B
(T)
DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3')polymer113381.21
3C
(P)
DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3')polymer72107.41
4D, E
(B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
5F
(B)
THYMIDINE-5'-TRIPHOSPHATEnon-polymer482.21Chemie (TTP)
6G, H, I
(B, T, P)
waterwater18.0256Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight52516.0
Non-Polymers*Number of molecules3
Total formula weight530.8
All*Total formula weight53046.7
*Water molecules are not included.

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PDB entries from 2025-07-30

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