3Q8H
Crystal structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphate synthase from burkholderia pseudomallei in complex with cytidine derivative EBSI01028
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | polymer | 183 | 19487.1 | 3 | UniProt (Q63T71) Pfam (PF02542) In PDB | Burkholderia pseudomallei (Pseudomonas pseudomallei) | MECDP-synthase, MECPS |
2 | A, B, C | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
3 | A, B | 5'-deoxy-5'-[(imidazo[2,1-b][1,3]thiazol-5-ylcarbonyl)amino]cytidine | non-polymer | 392.4 | 3 | Chemie (AO9) | |||
4 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
6 | water | water | 18.0 | 306 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 162 (UniProt: Q63T71)
PDB | External Database | Details |
---|---|---|
Met -20 | - | expression tag |
Ala -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
Met -12 | - | expression tag |
Gly -11 | - | expression tag |
Thr -10 | - | expression tag |
Leu -9 | - | expression tag |
Glu -8 | - | expression tag |
Ala -7 | - | expression tag |
Gln -6 | - | expression tag |
Thr -5 | - | expression tag |
Gln -4 | - | expression tag |
Gly -3 | - | expression tag |
Pro -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 58461.3 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1536.6 | |
All* | Total formula weight | 59998.0 |