3Q1S
HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Z13e1 Fab light chain | polymer | 212 | 23096.7 | 1 | Homo sapiens (human) | ||
| 2 | B (H) | Z13e1 Fab heavy chain | polymer | 230 | 24666.8 | 1 | Homo sapiens (human) | ||
| 3 | C (I) | Interleukin-22 | polymer | 151 | 17371.0 | 1 | UniProt (Q9GZX6) Pfam (PF14565) | Homo sapiens (human) | IL-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-TIF |
| 4 | D, E (L) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 2 | Chemie (IPA) | |||
| 5 | F, G, H, I, J... (L, H, I) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 6 | P, Q, R (L, H, I) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence modifications
I: 29 - 179 (UniProt: Q9GZX6)
| PDB | External Database | Details |
|---|---|---|
| Trp 64 | Ser 64 | engineered mutation |
| Asn 65 | Leu 65 | engineered mutation |
| Trp 66 | Ala 66 | engineered mutation |
| Asp 68 | Asn 68 | engineered mutation |
| Ile 69 | Asn 69 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 65134.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1041.1 | |
| All* | Total formula weight | 66175.6 |
