3Q1S
HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L | Z13e1 Fab light chain | polymer | 212 | 23096.7 | 1 | Homo sapiens (human) | ||
2 | H | Z13e1 Fab heavy chain | polymer | 230 | 24666.8 | 1 | Homo sapiens (human) | ||
3 | I | Interleukin-22 | polymer | 151 | 17371.0 | 1 | UniProt (Q9GZX6) Pfam (PF14565) In PDB | Homo sapiens (human) | IL-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-TIF |
4 | L | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 2 | Chemie (IPA) | |||
5 | L, H, I | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
6 | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence modifications
I: 29 - 179 (UniProt: Q9GZX6)
PDB | External Database | Details |
---|---|---|
Trp 64 | Ser 64 | engineered mutation |
Asn 65 | Leu 65 | engineered mutation |
Trp 66 | Ala 66 | engineered mutation |
Asp 68 | Asn 68 | engineered mutation |
Ile 69 | Asn 69 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 65134.5 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1041.1 | |
All* | Total formula weight | 66175.6 |