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3Q1I

Polo-like kinase I Polo-box domain in complex with FMPPPMSpSM phosphopeptide from TCERG1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase PLK1polymer23226755.51UniProt (P53350)
Pfam (PF00659)
Homo sapiens (human)Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13
2B
(E)
peptide from Transcription elongation regulator 1polymer111128.31UniProt (O14776)peptide from TCERG1
3C
(A)
PENTAETHYLENE GLYCOLnon-polymer238.31Chemie (1PE)
4D
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
5E
(A)
2-(2-METHOXYETHOXY)ETHANOLnon-polymer120.11Chemie (PG0)
6F, G
(A, E)
waterwater18.0192Chemie (HOH)
Sequence modifications
A: 371 - 594 (UniProt: P53350)
PDBExternal DatabaseDetails
Gly 1-expression tag
Pro 2-expression tag
Leu 3-expression tag
Gly 4-expression tag
Ser 5-expression tag
Pro 6-expression tag
Glu 7-expression tag
Phe 8-expression tag
E: 99 - 107 (UniProt: O14776)
PDBExternal DatabaseDetails
Ace 98-acetylation
Nh2 108-amidation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27883.8
Non-Polymers*Number of molecules3
Total formula weight464.5
All*Total formula weight28348.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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