3PXM
Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Monellin chain B/Monellin chain A chimeric protein | polymer | 97 | 11391.0 | 2 | UniProt (P02882) UniProt (P02881) | Dioscoreophyllum cumminsii (Serendipity berry) | Monellin chain II, Monellin chain I |
| 2 | C, D (A, B) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 50 (UniProt: P02882)
A, B: 53 - 96 (UniProt: P02881)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ala 37 | Val 37 | engineered mutation |
| Asn 49 | Glu 49 | conflict |
| Glu 50 | Asn 50 | conflict |
| Gly 51 | - | linker |
| Phe 52 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22782.0 | |
| All* | Total formula weight | 22782.0 |
