3PVM

Structure of Complement C5 in Complex with CVF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Complement C5	polymer	1676	188512.1	2	UniProt (P01031) Pfam (PF17790) Pfam (PF07677) Pfam (PF01759) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) Pfam (PF01821) Pfam (PF00207) Pfam (PF07678) Pfam (PF21309) In PDB	Homo sapiens (human)	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin, Complement C5 alpha' chain
2	B, D	Cobra venom factor	polymer	1642	184726.7	2	UniProt (Q91132) Pfam (PF17790) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) Pfam (PF01821) Pfam (PF00207) Pfam (PF21406) Pfam (PF07678) Pfam (PF21308) Pfam (PF07677) Pfam (PF01759) In PDB	Naja kaouthia (Monocled cobra)	CVF, Complement C3 homolog, Cobra venom factor alpha chain, Cobra venom factor gamma chain, Cobra venom factor beta chain
3	A, B, C, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	746477.7
Non-Polymers*	Number of molecules	6
	Total formula weight	1327.2
All*	Total formula weight	747804.9

*Water molecules are not included.