3PS5
Crystal structure of the full-length Human Protein Tyrosine Phosphatase SHP-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 6 | polymer | 595 | 67640.0 | 1 | UniProt (P29350) Pfam (PF00017) Pfam (PF00102) | Homo sapiens (human) | Hematopoietic cell protein-tyrosine phosphatase, Protein-tyrosine phosphatase 1C, PTP-1C, Protein-tyrosine phosphatase SHP-1, SH-PTP1 |
| 2 | B, C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | G (A) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A: 1 - 595 (UniProt: P29350)
| PDB | External Database | Details |
|---|---|---|
| Ser 453 | Cys 453 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 67640.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 480.3 | |
| All* | Total formula weight | 68120.3 |
