3PP7
Crystal structure of Leishmania mexicana pyruvate kinase in complex with the drug suramin, an inhibitor of glycolysis.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pyruvate kinase | polymer | 498 | 54336.7 | 2 | UniProt (Q27686) Pfam (PF00224) Pfam (PF02887) | Leishmania mexicana | PK |
| 2 | C (A) | pyrene-1,3,6,8-tetrasulfonic acid | non-polymer | 522.5 | 1 | Chemie (PTK) | |||
| 3 | D, J (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E, F, H, I (A, B) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 5 | G (B) | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID | non-polymer | 1297.3 | 1 | Chemie (SVR) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 436 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 108673.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2160.4 | |
| All* | Total formula weight | 110833.8 |
