3POZ
EGFR Kinase domain complexed with tak-285
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 327 | 37304.1 | 1 | UniProt (P00533) Pfam (PF07714) | Homo sapiens (human) | Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 |
| 2 | B, C, D (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E (A) | N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide | non-polymer | 548.0 | 1 | Chemie (03P) | |||
| 4 | F (A) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37304.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 836.1 | |
| All* | Total formula weight | 38140.3 |
