3PN1
Novel Bacterial NAD+-dependent DNA Ligase Inhibitors with Broad Spectrum Potency and Antibacterial Efficacy In Vivo
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA ligase | polymer | 318 | 35799.6 | 1 | UniProt (P43813) Pfam (PF01653) In PDB | Haemophilus influenzae | Polydeoxyribonucleotide synthase [NAD+] |
| 2 | A | 2-(butylsulfanyl)adenosine | non-polymer | 355.4 | 1 | Chemie (IVH) | |||
| 3 | A | 1-(2,4-dimethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide | non-polymer | 256.3 | 1 | Chemie (IWH) | |||
| 4 | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35799.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 611.7 | |
| All* | Total formula weight | 36411.3 |
