3PLF
Reverse Binding Mode of MetRD peptide complexed with c-Cbl TKB domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | MetRD peptide | polymer | 11 | 1379.3 | 2 | |||
| 2 | B, D (B, D) | E3 ubiquitin-protein ligase CBL | polymer | 329 | 38192.1 | 2 | UniProt (P22681) Pfam (PF02262) Pfam (PF02761) Pfam (PF02762) | Homo sapiens (human) | Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, RING finger protein 55, Signal transduction protein CBL |
| 3 | E, I (B, D) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | F, G, H, J (B, D) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 584 | Chemie (HOH) |
Sequence modifications
B, D: 25 - 351 (UniProt: P22681)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 79142.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 222.0 | |
| All* | Total formula weight | 79364.8 |
