3PIP
Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | RIBOSOMAL 23S RNA | polymer | 2880 | 933405.0 | 1 | GenBank (AE000513.1) | Deinococcus radiodurans R1 | |
| 2 | B (Y) | 5S ribosomal RNA | polymer | 123 | 39605.7 | 1 | GenBank (AE000513.1) | Deinococcus radiodurans R1 | |
| 3 | C (A) | 50S ribosomal protein L2 | polymer | 274 | 29976.6 | 1 | UniProt (Q9RXJ9) Pfam (PF00181) Pfam (PF03947) | Deinococcus radiodurans | |
| 4 | D (B) | 50S ribosomal protein L3 | polymer | 211 | 22477.2 | 1 | UniProt (Q9RXK2) Pfam (PF00297) | Deinococcus radiodurans | |
| 5 | E (C) | 50S ribosomal protein L4 | polymer | 205 | 22308.2 | 1 | UniProt (Q9RXK1) Pfam (PF00573) | Deinococcus radiodurans | |
| 6 | F (D) | 50S ribosomal protein L5 | polymer | 180 | 20379.9 | 1 | UniProt (Q9RXJ0) Pfam (PF00673) Pfam (PF00281) | Deinococcus radiodurans | |
| 7 | G (E) | 50S ribosomal protein L6 | polymer | 185 | 19613.6 | 1 | UniProt (Q9RSL3) Pfam (PF00347) | Deinococcus radiodurans | |
| 8 | H (F) | 50S ribosomal protein L11 | polymer | 144 | 14889.2 | 1 | UniProt (Q9RSS7) Pfam (PF03946) Pfam (PF00298) | Deinococcus radiodurans | |
| 9 | I (G) | 50S ribosomal protein L13 | polymer | 174 | 19223.2 | 1 | UniProt (Q9RXY1) Pfam (PF00572) | Deinococcus radiodurans | |
| 10 | J (H) | 50S ribosomal protein L14 | polymer | 134 | 14256.5 | 1 | UniProt (Q9RXJ2) Pfam (PF00238) | Deinococcus radiodurans | |
| 11 | K (I) | 50S ribosomal protein L15 | polymer | 156 | 16894.2 | 1 | UniProt (Q9RSK9) Pfam (PF00828) | Deinococcus radiodurans | |
| 12 | L (J) | 50S ribosomal protein L16 | polymer | 141 | 16126.0 | 1 | UniProt (Q9RXJ5) Pfam (PF00252) | Deinococcus radiodurans | |
| 13 | M (K) | 50S ribosomal protein L17 | polymer | 116 | 12926.1 | 1 | UniProt (Q9RSJ5) Pfam (PF01196) | Deinococcus radiodurans | |
| 14 | N (L) | 50S ribosomal protein L18 | polymer | 114 | 12163.9 | 1 | UniProt (Q9RSL2) Pfam (PF00861) | Deinococcus radiodurans | |
| 15 | O (M) | 50S ribosomal protein L19 | polymer | 166 | 18347.8 | 1 | UniProt (Q9RWB4) Pfam (PF01245) | Deinococcus radiodurans | |
| 16 | P (N) | 50S ribosomal protein L20 | polymer | 118 | 13991.3 | 1 | UniProt (Q9RSW7) Pfam (PF00453) | Deinococcus radiodurans | |
| 17 | Q (O) | 50S ribosomal protein L21 | polymer | 100 | 11165.7 | 1 | UniProt (Q9RY64) Pfam (PF00829) | Deinococcus radiodurans | |
| 18 | R (P) | 50S ribosomal protein L22 | polymer | 134 | 15190.9 | 1 | UniProt (Q9RXJ7) Pfam (PF00237) | Deinococcus radiodurans | |
| 19 | S (Q) | 50S ribosomal protein L23 | polymer | 95 | 10539.2 | 1 | UniProt (Q9RXK0) Pfam (PF00276) | Deinococcus radiodurans | |
| 20 | T (R) | 50S ribosomal protein L24 | polymer | 115 | 12384.4 | 1 | UniProt (Q9RXJ1) Pfam (PF00467) Pfam (PF17136) | Deinococcus radiodurans | |
| 21 | U (S) | 50S ribosomal protein L25 | polymer | 237 | 25415.4 | 1 | UniProt (Q9RX88) Pfam (PF01386) Pfam (PF14693) | Deinococcus radiodurans | General stress protein CTC |
| 22 | V (T) | 50S ribosomal protein L27 | polymer | 91 | 9609.1 | 1 | UniProt (Q9RY65) Pfam (PF01016) | Deinococcus radiodurans | |
| 23 | W (U) | 50S ribosomal protein L28 | polymer | 81 | 8982.6 | 1 | UniProt (Q9RRG8) Pfam (PF00830) | Deinococcus radiodurans | |
| 24 | X (V) | 50S ribosomal protein L29 | polymer | 67 | 7775.0 | 1 | UniProt (Q9RXJ4) Pfam (PF00831) | Deinococcus radiodurans | |
| 25 | Y (W) | 50S ribosomal protein L30 | polymer | 55 | 6079.2 | 1 | UniProt (Q9RSL0) Pfam (PF00327) | Deinococcus radiodurans | |
| 26 | Z (Z) | 50S ribosomal protein L32 | polymer | 60 | 6810.0 | 1 | UniProt (P49228) Pfam (PF01783) | Deinococcus radiodurans | |
| 27 | AA (1) | 50S ribosomal protein L33 | polymer | 55 | 6374.5 | 1 | UniProt (Q9RSS4) Pfam (PF00471) | Deinococcus radiodurans | |
| 28 | BA (2) | 50S ribosomal protein L34 | polymer | 47 | 5626.6 | 1 | UniProt (Q9RSH2) Pfam (PF00468) | Deinococcus radiodurans | |
| 29 | CA (3) | 50S ribosomal protein L35 | polymer | 66 | 7448.1 | 1 | UniProt (Q9RSW6) Pfam (PF01632) | Deinococcus radiodurans | |
| 30 | DA (4) | 50S ribosomal protein L36 | polymer | 37 | 4322.3 | 1 | UniProt (Q9RSK0) Pfam (PF00444) | Deinococcus radiodurans | |
| 31 | EA (X) | N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl]-2-oxopropanamide | non-polymer | 459.5 | 1 | Chemie (LC2) | |||
| 32 | FA (X) | Lankamycin | non-polymer | 831.0 | 1 | Chemie (LMA) | |||
| 33 | AB, AC, BB, BC, CB... (X, I, U) | MAGNESIUM ION | non-polymer | 24.3 | 73 | Chemie (MG) | |||
| 34 | AD, BD, CD, ZC (X) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 35 | DD, ED, FD, GD, HD (X) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 1364307.4 | |
| Non-Polymers* | Number of molecules | 84 |
| Total formula weight | 3336.2 | |
| All* | Total formula weight | 1367643.6 |
