3PIP
Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | RIBOSOMAL 23S RNA | polymer | 2880 | 933405.0 | 1 | GenBank (AE000513.1) | Deinococcus radiodurans R1 | |
| 2 | B (Y) | 5S ribosomal RNA | polymer | 123 | 39605.7 | 1 | GenBank (AE000513.1) | Deinococcus radiodurans R1 | |
| 3 | C (A) | 50S ribosomal protein L2 | polymer | 274 | 29976.6 | 1 | UniProt (Q9RXJ9) Pfam (PF00181) Pfam (PF03947) | Deinococcus radiodurans | |
| 4 | D (B) | 50S ribosomal protein L3 | polymer | 211 | 22477.2 | 1 | UniProt (Q9RXK2) Pfam (PF00297) | Deinococcus radiodurans | |
| 5 | E (C) | 50S ribosomal protein L4 | polymer | 205 | 22308.2 | 1 | UniProt (Q9RXK1) Pfam (PF00573) | Deinococcus radiodurans | |
| 6 | F (D) | 50S ribosomal protein L5 | polymer | 180 | 20379.9 | 1 | UniProt (Q9RXJ0) Pfam (PF00673) Pfam (PF00281) | Deinococcus radiodurans | |
| 7 | G (E) | 50S ribosomal protein L6 | polymer | 185 | 19613.6 | 1 | UniProt (Q9RSL3) Pfam (PF00347) | Deinococcus radiodurans | |
| 8 | H (F) | 50S ribosomal protein L11 | polymer | 144 | 14889.2 | 1 | UniProt (Q9RSS7) Pfam (PF03946) Pfam (PF00298) | Deinococcus radiodurans | |
| 9 | I (G) | 50S ribosomal protein L13 | polymer | 174 | 19223.2 | 1 | UniProt (Q9RXY1) Pfam (PF00572) | Deinococcus radiodurans | |
| 10 | J (H) | 50S ribosomal protein L14 | polymer | 134 | 14256.5 | 1 | UniProt (Q9RXJ2) Pfam (PF00238) | Deinococcus radiodurans | |
| 11 | K (I) | 50S ribosomal protein L15 | polymer | 156 | 16894.2 | 1 | UniProt (Q9RSK9) Pfam (PF00828) | Deinococcus radiodurans | |
| 12 | L (J) | 50S ribosomal protein L16 | polymer | 141 | 16126.0 | 1 | UniProt (Q9RXJ5) Pfam (PF00252) | Deinococcus radiodurans | |
| 13 | M (K) | 50S ribosomal protein L17 | polymer | 116 | 12926.1 | 1 | UniProt (Q9RSJ5) Pfam (PF01196) | Deinococcus radiodurans | |
| 14 | N (L) | 50S ribosomal protein L18 | polymer | 114 | 12163.9 | 1 | UniProt (Q9RSL2) Pfam (PF00861) | Deinococcus radiodurans | |
| 15 | O (M) | 50S ribosomal protein L19 | polymer | 166 | 18347.8 | 1 | UniProt (Q9RWB4) Pfam (PF01245) | Deinococcus radiodurans | |
| 16 | P (N) | 50S ribosomal protein L20 | polymer | 118 | 13991.3 | 1 | UniProt (Q9RSW7) Pfam (PF00453) | Deinococcus radiodurans | |
| 17 | Q (O) | 50S ribosomal protein L21 | polymer | 100 | 11165.7 | 1 | UniProt (Q9RY64) Pfam (PF00829) | Deinococcus radiodurans | |
| 18 | R (P) | 50S ribosomal protein L22 | polymer | 134 | 15190.9 | 1 | UniProt (Q9RXJ7) Pfam (PF00237) | Deinococcus radiodurans | |
| 19 | S (Q) | 50S ribosomal protein L23 | polymer | 95 | 10539.2 | 1 | UniProt (Q9RXK0) Pfam (PF00276) | Deinococcus radiodurans | |
| 20 | T (R) | 50S ribosomal protein L24 | polymer | 115 | 12384.4 | 1 | UniProt (Q9RXJ1) Pfam (PF00467) Pfam (PF17136) | Deinococcus radiodurans | |
| 21 | U (S) | 50S ribosomal protein L25 | polymer | 237 | 25415.4 | 1 | UniProt (Q9RX88) Pfam (PF01386) Pfam (PF14693) | Deinococcus radiodurans | General stress protein CTC |
| 22 | V (T) | 50S ribosomal protein L27 | polymer | 91 | 9609.1 | 1 | UniProt (Q9RY65) Pfam (PF01016) | Deinococcus radiodurans | |
| 23 | W (U) | 50S ribosomal protein L28 | polymer | 81 | 8982.6 | 1 | UniProt (Q9RRG8) Pfam (PF00830) | Deinococcus radiodurans | |
| 24 | X (V) | 50S ribosomal protein L29 | polymer | 67 | 7775.0 | 1 | UniProt (Q9RXJ4) Pfam (PF00831) | Deinococcus radiodurans | |
| 25 | Y (W) | 50S ribosomal protein L30 | polymer | 55 | 6079.2 | 1 | UniProt (Q9RSL0) Pfam (PF00327) | Deinococcus radiodurans | |
| 26 | Z (Z) | 50S ribosomal protein L32 | polymer | 60 | 6810.0 | 1 | UniProt (P49228) Pfam (PF01783) | Deinococcus radiodurans | |
| 27 | AA (1) | 50S ribosomal protein L33 | polymer | 55 | 6374.5 | 1 | UniProt (Q9RSS4) Pfam (PF00471) | Deinococcus radiodurans | |
| 28 | BA (2) | 50S ribosomal protein L34 | polymer | 47 | 5626.6 | 1 | UniProt (Q9RSH2) Pfam (PF00468) | Deinococcus radiodurans | |
| 29 | CA (3) | 50S ribosomal protein L35 | polymer | 66 | 7448.1 | 1 | UniProt (Q9RSW6) Pfam (PF01632) | Deinococcus radiodurans | |
| 30 | DA (4) | 50S ribosomal protein L36 | polymer | 37 | 4322.3 | 1 | UniProt (Q9RSK0) Pfam (PF00444) | Deinococcus radiodurans | |
| 31 | EA (X) | N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl]-2-oxopropanamide | non-polymer | 459.5 | 1 | Chemie (LC2) PubChem (177552479) PubChem (159955) PubChem (422576) PubChem (25199831) PubChem (49867228) PubChem (52947678) PubChem (53298613) PubChem (5458309) PubChem (155925974) PubChem (6037480) PubChem (6440871) PubChem (10095732) PubChem (16058267) PubChem (98520677) PubChem (98520679) PubChem (98520681) PubChem (98394853) PubChem (5475467) PubChem (12302144) PubChem (15966498) PubChem (145627868) PubChem (146158309) PubChem (159297780) PubChem (162943617) PubChem (162943618) PubChem (162943619) PubChem (162943620) PubChem (169543501) | |||
| 32 | FA (X) | Lankamycin | non-polymer | 831.0 | 1 | Chemie (LMA) PubChem (52945232) | |||
| 33 | AB, AC, BB, BC, CB... (X, I, U) | MAGNESIUM ION | non-polymer | 24.3 | 73 | Chemie (MG) PubChem (888) | |||
| 34 | AD, BD, CD, ZC (X) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) PubChem (813) | |||
| 35 | DD, ED, FD, GD, HD (X) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) PubChem (923) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 1364307.4 | |
| Non-Polymers* | Number of molecules | 84 |
| Total formula weight | 3336.2 | |
| All* | Total formula weight | 1367643.6 |
