3PG7
Crystal structure of the H. sapiens NF1 SEC-PH domain (del1750 mutant)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Neurofibromin | polymer | 256 | 29330.6 | 2 | UniProt (P21359) Pfam (PF13716) Pfam (PF21877) | Homo sapiens (human) | Neurofibromatosis-related protein NF-1, Neurofibromin truncated |
| 2 | C, D (A, B) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 2 | Chemie (PTY) | |||
| 3 | E, F (B) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 2 | Chemie (POP) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence modifications
A, B: 1560 - 1815 (UniProt: P21359)
| PDB | External Database | Details |
|---|---|---|
| - | Lys 1771 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58661.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1820.0 | |
| All* | Total formula weight | 60481.1 |
