3PFP
Structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis in complex with an active site inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG | polymer | 464 | 50828.4 | 2 | UniProt (O53512) Pfam (PF01474) | Mycobacterium tuberculosis | DAHP synthetase, phenylalanine-repressible |
| 2 | C, F (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, J (A, B) | (2S)-2,7-bis(phosphonooxy)heptanoic acid | non-polymer | 322.1 | 2 | Chemie (035) | |||
| 4 | E, G (A, B) | (2R)-2,7-bis(phosphonooxy)heptanoic acid | non-polymer | 322.1 | 2 | Chemie (036) | |||
| 5 | H (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | I (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | K, L (A, B) | water | water | 18.0 | 554 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 462 (UniProt: O53512)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 101656.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1530.0 | |
| All* | Total formula weight | 103186.8 |
