3PFH
X-Ray crystal structure the N,N-dimethyltransferase TylM1 from Streptomyces fradiae in complex with SAH and dTDP-Quip3N
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | N-methyltransferase | polymer | 263 | 28537.9 | 2 | UniProt (P95748) Pfam (PF13649) In PDB | Streptomyces fradiae | |
2 | A, D | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
3 | A, D | [(3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate | non-polymer | 547.3 | 2 | Chemie (T3Q) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
5 | water | water | 18.0 | 478 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 255 (UniProt: P95748)
PDB | External Database | Details |
---|---|---|
Leu 256 | - | expression tag |
Glu 257 | - | expression tag |
His 258 | - | expression tag |
His 259 | - | expression tag |
His 260 | - | expression tag |
His 261 | - | expression tag |
His 262 | - | expression tag |
His 263 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 57075.8 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1925.6 | |
All* | Total formula weight | 59001.3 |