3PE4
Structure of human O-GlcNAc transferase and its complex with a peptide substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | polymer | 723 | 80974.5 | 2 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) | Homo sapiens (human) | O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine transferase 110 kDa subunit |
| 2 | B, D (B, D) | Casein kinase II subunit alpha | polymer | 14 | 1398.6 | 2 | UniProt (P68400) | Homo sapiens | CK II alpha |
| 3 | E, H (A, C) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (57448939) PubChem (53486216) PubChem (60098857) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (1158) PubChem (6031) PubChem (3084486) PubChem (6101632) PubChem (6604175) PubChem (11811538) PubChem (12049241) | |||
| 4 | F, G, I (A, B, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 854 | Chemie (HOH) |
Sequence modifications
A, C: 313 - 1031 (UniProt: O15294)
B, D: 14 - 26 (UniProt: P68400)
| PDB | External Database | Details |
|---|---|---|
| Gly 309 | - | expression tag |
| Pro 310 | - | expression tag |
| Gly 311 | - | expression tag |
| Ser 312 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Tyr 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 164746.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1096.5 | |
| All* | Total formula weight | 165842.7 |
