3PBA
Crystal structure of PPARgamma ligand binding domain in complex with monosulfate tetrabromo-bisphenol A (MonoTBBPA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peroxisome proliferator-activated receptor gamma | polymer | 286 | 32622.7 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-gamma, Nuclear receptor subfamily 1 group C member 3 |
| 2 | A | 2,6-dibromo-4-[2-(3,5-dibromo-4-hydroxyphenyl)propan-2-yl]phenyl hydrogen sulfate | non-polymer | 623.9 | 1 | Chemie (ZXG) | |||
| 3 | B | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 1 | Chemie (PGO) | |||
| 4 | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A, B: 196 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 192 | - | expression tag |
| Ser 193 | - | expression tag |
| His 194 | - | expression tag |
| Met 195 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65245.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 700.0 | |
| All* | Total formula weight | 65945.5 |
