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3PBA

Crystal structure of PPARgamma ligand binding domain in complex with monosulfate tetrabromo-bisphenol A (MonoTBBPA)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues17
DetailsBINDING SITE FOR RESIDUE ZXG A 1
ChainResidue
AHOH139
AILE341
ASER342
APHE363
AMET364
ALYS367
AHOH483
AHOH492
AHOH493
ACYS285
AGLN286
AARG288
ASER289
ATYR327
ALEU330
AVAL339
ALEU340

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PGO B 6128
ChainResidue
ALYS240
ALYS244
BASN312

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
ChainResidueDetails
AGLN286
AHIS323
AHIS449
BHIS449
BTYR473
ATYR473
BGLN286
BHIS323

site_idSWS_FT_FI2
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649
ChainResidueDetails
ALYS224
BLYS224

218500

PDB entries from 2024-04-17

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