3PB3

Structure of an Antibiotic Related Methyltransferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	16S rRNA methylase	polymer	225	25823.6	2	UniProt (A8C927)	Escherichia coli
2	C, D (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
3	E, F (A, B)	water	water		18.0	321	Chemie (HOH)

Sequence modifications

A, B: 1 - 219 (UniProt: A8C927)

PDB	External Database	Details
Met 31	Leu 31	engineered mutation
Met 90	Leu 90	engineered mutation
Met 128	Leu 128	engineered mutation
Met 196	Leu 196	engineered mutation
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51647.2
Non-Polymers*	Number of molecules	2
	Total formula weight	768.8
All*	Total formula weight	52416.0

*Water molecules are not included.