3PB0

Characterisation of the first monomeric dihydrodipicolinate synthase variant reveals evolutionary insights

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Dihydrodipicolinate synthase	polymer	300	32927.8	4	UniProt (Q9X1K9) Pfam (PF00701)	thermotoga maritima	DHDPS
2	E, F, G (A, C, D)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3	H, I, J, K (A, B, C, D)	water	water		18.0	1064	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 294 (UniProt: Q9X1K9)

PDB	External Database	Details
Gly -5	-	expression tag
Ile -4	-	expression tag
Asp -3	-	expression tag
Pro -2	-	expression tag
Phe -1	-	expression tag
Thr 0	-	expression tag
Ala 166	Asp 166	engineered mutation
Ala 167	Ile 167	engineered mutation
Ala 168	Asp 168	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	131711.2
Non-Polymers*	Number of molecules	3
	Total formula weight	288.2
All*	Total formula weight	131999.4

*Water molecules are not included.