3P8Z
Dengue Methyltransferase bound to a SAM-based inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Non-structural protein 5 | polymer | 267 | 30069.6 | 2 | UniProt (C1KBQ3) Pfam (PF01728) UniProt (by SIFTS) (P27915) In PDB | Dengue virus 3 | Mtase |
| 2 | A | (S)-2-amino-4-(((2S,3S,4R,5R)-5-(6-(3-chlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)butanoic acid | non-polymer | 509.0 | 1 | Chemie (36A) | |||
| 3 | C | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | water | water | 18.0 | 718 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 262 (UniProt: C1KBQ3)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60139.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 893.4 | |
| All* | Total formula weight | 61032.6 |
